Robin Freedenfeld grew up in Verona, New Jersey. She studied at Rochester Institute of Technology, graduating in 1973 with a major focus in etching and lithography.

After college, Freedenfeld opened three printmaking workshops: the first in Boston, then Chicago, and a third in Northampton, Massachusetts. In Northampton, Freedenfeld met many artists who influenced her decision to paint. In 1984, following an exhibition of paintings with a group of friends at the Wistariahurst Museum in Holyoke, Massachusetts, an article appeared in The New England Monthly entitled "Fertile Valley," in which the author coined the term "Valley Realists" to describe the group of painters based in the Connecticut River Valley. Freedenfeld has continued to embrace this realist tradition. Although not photo realistic, her paintings are a combination of photography, imagination, and direct inspiration from life.

Freedenfeld has had 10 solo exhibitions, including a 1990 show at the Museum of Fine Arts in Springfield, MA. She has been included in many group exhibitions, including shows at The Fitchburg Museum, The Deland Museum of Art, The Butler Institute of American Art, The Wistariahurst Museum, The Art Institute of Boston, and The DeCordova Dana Museum. Freedenfeld's work is included in many permanent collections, including those of the Bank of Boston, the Chemical Bank of New York, Illinois Bell Telephone, Northwestern University, and the University of Maine. In 1990, Freedenfeld received the Massachusetts Artist Fellowship, and was featured in a video documentary, "Eye of the Realist." Freedenfeld's work has also been featured several times in American Artist Magazine.